Achievements

PROF. B.P. SRINIVASAN

Director (Officiating) DIPSAR, Professor

(Pharmacology); Head, Pharmacology & Quality Assurance


List of Publications 2012-13

  • Vildagliptin selectively ameliorates GLP- 1, GLUT-4, SREBP-1c mRNA levels and stimulates β-Cell proliferation resulting in improved glucose homeostasis in rats with streptozotocin induced diabetes. Atul sureshrao Akarte, B.P. Srinivasan, Sonia Gandhi. Journal of diabetes and its complications, 2012.
  • Effective blockade of RAAS by combination of aliskiren and olmesartan improves glucose homeostasis, glomerular filtration rate along with renal variables in streptozotocin induced diabetic rats. Sonia Gandhi, B P Srinivasan, Atul Sureshrao Akarete. European Journal of Pharmaceutical Sciences, 46 (2012) 32–42.
  • Aqueous extract of tamarind seeds selectively increases GLUT-2, GLUT-4, and Islets’[Ca2+]I levels and stimulates beta-cell proliferation in streptozotocin- induced rats.Sushant Shivdas Sole, Bhartur parthsarthy Srinivasan. Nutrition Research- Accepted -doi:10.1016/j.nutres.2012.06.015- In press.
  • Chronic DPP-IV inhibition with PKF-275-055 attenuates inflammation and improves gene expressions responsible for insulin secretion in streptozotocin induced diabetic rats” Atul sureshrao Akarte, Srinivasan BP, Sonia Gandhi, Sushant sole. Manuscripted accepted in European Journal of Pharmaceutical Sciences. – 2012, 47, 456-463.
  • Tamarind Seed Extract Attenuates Cardiovascular Impairment Superimposed onType II Diabetic Rats. Sushant Shivdas Sole, Bhartu Parthsarthy Srinivasan. Inventi RapidEthnopharmacology Vol. 2012, Issue 3. In press.
  • Gandhi S., Srinivasan B.P., Akarte A.S. 2013. Potential nephrotoxic effects producedby steroidal saponins from hydro alcoholic extract of Tribulus terrestris in STZ induceddiabetic rats. Toxicological mechanisms and methods. In Press.
  • Gandhi S., Srinivasan B.P., Akarte A.S. 2013 An experimental assessment of toxic potentialof nanoparticle preparation of heavy metals in streptozotocin induced diabetes. Experimental and Toxicologic Pathology. In Press
  • Kumar, B., Gupta, S.K., Srinivasan, B.P.,Nag, T.C., Srivastava, S., Saxena, R., Jha, K.A. 2013. Hesperetin rescues retinal oxidative stress, neuroinflammation and apoptosis in diabetic rats. Microvascular Research 87 , pp.65-74
  • Nagar, A., Kumar, A., Gullaiya, S., Dubey, V., Singh, V., Tiwari, P., Meena, V., Srinivasan, B.P. 2013. Spasmolytic effect of novel antagonists of the adenosine A2 receptor in isolated guinea pig tracheal smooth muscle . Biomedicine and Aging Pathology 3 (1) , pp. 31-35
  • Kumar, B., Gupta, S.K., Srinivasan, B.P.,Nag, T.C., Srivastava, S., Saxena, R. 2012. Hesperetin ameliorates hyperglycemia induced retinal vasculopathy via anti-angiogeniceffects in experimental diabetic rats. Vascular Pharmacology 57 (5-6) , pp. 201-207.Shukla, A., Srinivasan, B.P. 2012. 16,17-Dihydro-17b-hydroxy isomitraphylline alkaloid as an inhibitor of DPP-IV, and its effect on incretin hormone and β-cell proliferation in diabetic rat. European Journal of Pharmaceutical Sciences 47 (2), pp. 512-519
  • Kumar Sharma, D., Manral, A., Saini, V.,Singh, A., Srinivasan, B.P., Tiwari, M. 2012. Novel diallyldisulfide analogs ameliorate cardiovascular remodeling in rats with L-NAME-induced hypertension. 2012. European Journal of Pharmacology 691 (1-3), pp. 198-208
  • Sharma, A.K., Sharma, A., Kumari, R.,Kishore, K., Sharma, D., Srinivasan, B.P.,Sharma, A.,Munajjam, A. 2012. Sitagliptin, sitagliptin and metformin, or sitagliptin and amitriptyline attenuate streptozotocin-nicotinamide induced diabetic neuropathy in rats. Journal of Biomedical Research 26 (3) , pp. 200-210

PROF. S.K. GUPTA

Professor Emeritus, Clinical Research (DIPSAR),

Advisor to Pharmacovigilance Program of India (PvPI)


MAJOR ACHIEVEMENTS

  • International collaboration under UK-INDIA Education and Research initiative (UKIERI) was established between University of Manchester, UK & DIPSAR (University of Delhi) UKIERI Award – 2013
  • Mr Binit Kumar, PhD Student, received Association for Research in Vision & Ophthalmology, USA (ARVO) International Travel Fellowship Award for Annual Meeting being held at Seattle, Washington, USA (May 2013).
  • Elected Unanimously President ISPOR, India Chapter

PUBLICATIONS

  • Binit Kumar, S K Gupta, B P Srinivasan, T C Nag, Rohit Saxena, Sushma Srivastava, Kumar Abhiram Jha. Hesperetin rescues retinal oxidative stress, neuroinflammation and apoptosis in diabetic rats. Microvasc Res. 2013, pii: S0026-2862(13)00003-4.doi:10.1016/j.mvr.2013.01.002.
  • S K Gupta, Binit Kumar, BP Srinivasan, TC Nag, Sushma Srivastava, Rohit Saxena, Ashutosh Aggarwal. Retinoprotective Effects of Moringa oleifera Via Antioxidant,Anti-Inflammatory, and Anti-Angiogenic Mechanisms in Streptozotocin-Induced Diabetic Rats. J Ocul Pharmacol Ther. 2012 Dec 10. doi:10.1089/jop.2012.0089.
  • Binit Kumar, S K Gupta, B P Srinivasan, T C Nag, Rohit Saxena, Sushma Srivastava: Hesperetin ameliorates hyperglycemia induced retinal vasculopathy via anti-angiogenic effects in experimental diabetic rats. Vascul. Pharmacol. 2012; 57, 201-07.
  • S K Gupta and Binit Kumar. Recent Developments in Clinical Research (India). The Pharma Review, Nov – Dec 2012.
  • Agrawal SS, Naqvi S, Gupta SK, Srivastava S. Prevention and management of diabeti retinopathy in STZ diabetic rats by Tinospora cordifolia and its molecular mechanisms. Food Chem Toxicol. 2012 Jun 9;50(9):3126-3132.

PROF. D.P. PATHAK

Professor, Pharmaceutical Chemistry

  • Life science conclave 2012. Promoting business innovation to drive growth in life sciences organized by confederation of Indian Industry in Stein Auditorium at Indian Habitat Centre, New Delhi on 11-12 Dec, 2012.
  • Chaired poster session Publications in International Conference of Pharmacoeconomics and Outcomes Research organized by ISPOR India chapter in Jacaranda Hall at Indian Habitat Centre, New Delhi on 23-24 Nov 2012.
  • ASSOCHAM Summit on women and child health products and strategies with a difference organized at hotel the Royal Plaza New Delhi on Nov 1, 2012
  • 10th Knowledge Millennium Summit organized by ASSOCHAM on curing the incurables: sharing of innovations at VigyanBhavan, New Delhi on Jan 16th 2013.
  • IPGA National Convention-2012 on the theme “The Future of Pharmacist-A Health Care Professional” jointly organized by IPGA, Kurukshetra chapter an Institute of Pharm Sci, Kurukshetra University on 17- 18th Nov 2012.
  • Acted as a judge for debate competition in celebration of national voters day on 25/01/2013 organised by District Election Officer (South) GNCT of Delhi, Saket, New Delhi.

PUBLICATIONS

  • Prabodh Chander Sharma, AlkaSinhman, Archana Sharma, Harish Razak and Dharam Pal Pathak. Medical significance of benzothiazolescaffolds: an insight view. Journal of Enzyme Inhibition and Medicinal Chemistry 1(11), 1-27, 2012.
  • MS Ashraf, DP Pathak. Synthesis of 7-azaindole derivatives and their evaluation for analgesic activity. IJPFR 1(3), 1-8, 2012.
  • VeenaKathuria, DPPathak Synthesis and anticonvulsant activity of some n-substitutedphthalimide analogues. The Pharma Innovation, 1(10) 55-59, 2012.
  • Sunil Kumar, DP Pathak. Synthesis, characterization and evaluation for anticonvulsant activityofacetylnaphthaleneand substituted acetylnaphthalene derivatives of heterocyclic compounds. The Pharma Innovation 1(11), 90-101, 2013.
  • SuchetaOhlan, Sanju Nanda and Dharam Pal Pathak. Synthesis and characterization in-vitro
  • hydrolysis and pharmacodynamics profile of potential and novel mutual prodrugs of N- (2,
  • 3-xylylanthranilic acid). Medchem Research 2013
  • Kuldeep Kumar, Prof. (Dr.) D.P. Pathak. Synthesis, characterization and evaluation for antimicrobial activity of 2-substituted benzimidazole derivatives. The Pharma Innovation 1(9),44-50(2012).

Prof. (Dr.) D.K Majumdar

Professor (Pharmaceutics)


PUBLICATIONS

  • Pawar P, Katara R, Mishra S, Majumdar DK. Topical ocular delivery of fluoroquinolones.Expert Opin Drug Deliv. 2013 May;10(5):691- 711
  • Katara R, Majumdar DK Eudragit RL 100-based nanoparticulate system of aceclofenac for ocular delivery. Colloids Surf B Biointerfaces. 2013 Mar 1;103: 455-62.
  • Thakral NK, Ray AR, Jacobsen J, Bar-Shalom D, Eriksson AH, Majumdar DK. Colon targeting of fluticasone propionate inclusion complex: A novel approach in inflammatory bowel disease Journal of Inclusion Phenomena and Macrocyclic Chemistry. 2013; 75 (1-2):175-184.
  • Thakral S, Thakral NK, Majumdar DK. Eudragit®: A technology evaluation Expert Opinion on Drug Delivery. 2013; 10 (1): 131- 149.
  • Aerry S, De A, Kumar A, Saxena A, Majumdar DK, Mozumdar S. Synthesis copolymers for drug delivery. J Biomed Mater Res A. 2012 Dec 18.
  • Sharma M, Sharma V, Panda AK, Majumdar DK.Development of enteric submicron particles formulation of α-amylase for oral delivery. Pharm Dev Technol. 2013 May-Jun;18(3):560-569.
  • Kaithwas G, Majumdar DK. In vitro antioxidant and in vivo antidiabetic, antihyperlipidemic activity of linseed oil against streptozotocin-induced toxicity in albino rats. European Journal of Lipid Science and Technology.2012; 114 (11): 1237-1245.
  • Expert Committee member - Acted as an Expert Member for Ranbaxy Science Scholars 2012:
  • Scholarship Awards for Young Scientists.

DR. SHARAD WAKODE

Associate Professor, Pharmaceutical Chemistry

  • Conferences attended: 01 National Conference on Use of Animals and Alternatives in Biomedical Research with Special referenceto Drug Discovery and Drug Development (Under the aegis of Committee for the purpose of Control and Supervision of Experiments on Animals (CPCSEA), February 14 -15, 2013. Organized by: Amity University, NOIDA(U.P.).

DR. (Mrs.) MEENAKSHI K. CHAUHAN

Assistant Professor, Pharmaceutics

PUBLICATIONS

  • Tanu Goyal, Ashwani Singh Rawat and Meenakshi Chauhan. Pharmacosomes Opening new doors for drug delivery. International Journal of Pharmacy and Pharmaceutical Sciences. Vol 4, Suppl 3, 2012
  • Formulation, characterization and In-vitro- In vivo evaluation of flurbiprofen-loaded
  • Nanostructured lipid carriers for transdermal delivery. Jitender Kawadkar, Meenakshi
  • K.Chauhan. Drug Development Ind. Pharmacy. Drug Dev Ind Pharm 39(4):569-78 (2013)